As a group, women with polycystic ovary syndrome (PCOS) are at risk for diabetes in greater numbers and at an earlier age than the general population. PCOS may also increase the risk associated with high blood pressure and high cholesterol, especially among obese women. Linking these risks together in an assessment of metabolic syndrome provides a more complete approach to identify women with PCOS who may need therapies to reduce serious long-term health hazards.
Definitions of metabolic syndrome vary somewhat among organizations, but all current definitions include measures of central obesity, glucose intolerance, hypertension( high blood pressure), and dyslipidemia ( high cholesterol). These 4 common elements have been closely associated with the development of both coronary heart disease and peripheral vascular disease. According to the US census in 2000, about 47 million residents had metabolic syndrome at that time. The problem is growing; the data show that the age-adjusted prevalence of metabolic syndrome increased in women by 23% during the last decade of the 20th century. The risk of metabolic syndrome rises with age, but the incidence is also increasing among American teenagers. Ethnicity also influences the prevalence of metabolic syndrome, which is found more frequently in black and Mexican-American women.
Some common signs of PCOS include irregular periods ( especially lack of period related to lack of ovulation), infertility, endometrial cancer, acne, hirsutism ( growth of hair on face), difficulty losing weight, early-onset diabetes and cardiovascular disease. Blood pressure should be monitored monthly and medication may be needed. Because more than 60% of US women are overweight or obese, measurement of waist circumference is being recommended in addition to the customary “weigh-in.” For women of northern European descent, a circumference of more than 88 cm defines central obesity, but women of other ethnicities have different cutoffs.
If you suspect that you may have some symptoms of PCOS see your primary care practitioner or women’s health practitioner and they will run some labs including cholesterol levels, hormone levels ( testosterone, FSH, LH, estradiol), glucose tolerance tests and possibly insulin. They will also take your blood pressure and determine your BMI. Treatment will vary based upon the symptoms you have.
THERAPEUTIC LIFESTYLE CHANGESBecause lifestyle interventions improve all elements of the metabolic syndrome, they constitute first-line therapy and should be included in all treatment plans. The focus of these therapeutic lifestyle changes is weight loss, with an emphasis on diet and physical activity. A 10% weight loss will often reduce insulin resistance, improve high-density lipoprotein cholesterol (HDL-C), and lower low-density lipoprotein cholesterol (LDL-C) and triglycerides. Menstrual cycles and ovulation cycles can return with modest (10% to 15%) weight loss.
Weight LossThe efficacy of proper diet is undisputable. The risk of cardiovascular disease (CVD) can be reduced by more than 50% by maintaining a healthy body weight while engaging in regular physical activity. In addition, reducing body weight by only 7% yields a 58% reduction in the risk of type 2 diabetes. However, PCOS women have unique challenges achieving and maintaining healthy weights. Because they consume less energy metabolizing their food, they often require a lower-calorie diet than other women do to lose weight.
Bariatric surgery has been found to be immensely helpful in the resolution of PCOS. It can eliminate type 2 Diabetes by 93%, reduce hirsutism by 79% and 100% resolution of menstrual dysfunction. ( see picture below)
“Metabolic Woman”
Bariatric surgery is known to be one of the most effective and longest lasting treatments for morbid obesity. It can also positively affect the following obesity-related conditions: Reprinted with permission of The Cleveland Clinic Center for Medical Art & Photography © 2007. All Rights Reserved

Exercise
Exercise must be strongly recommended to help maintain long-term weight loss even after bariatric surgery. The addition of exercise to calorie restriction improves body composition. Patients with metabolic risk should be advised to engage in moderately intense physical activity for at least 30 minutes a day (preferably 45 to 60 minutes) for at least 5 days per week.
If you suspect you may have PCOS follow up with your health care provider. If you have been diagnosed with PCOS and are struggling to lose weight with a BMI of 35 and higher, bariatric surgery may be an option to consider. If you have any questions feel free to call our office to set up a consult to learn more about the lap band or bypass to help resolve your PCOS.
Labels: PCOS